We are interested in the cellular function and regulatory mechanisms of redox-regulated chaperones in eukaryotes and aim to understand the interplay between redox and protein homeostasis in maintaining a healthy proteome during stress conditions and aging.

Ulrich K, Farkas A, Chan O, Katamanin O, Schwappach B, and Jakob U (2022) From guide to guard – Activation mechanism of the stress-sensing chaperone Get3. Mol Cell, 82(17):3226-3238.e7. DOI: 10.1016/j.molcel.2022.06.015