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Mathematisch-Naturwissenschaftliche FakultätInstitut für Biochemie - AG Prof. Ulrich

Publications

  • Ulrich K (2023) Redox-regulated chaperones in cell stress responses. Biochem Soc Trans BST20221304

  • Ulrich K, Farkas A, Chan O, Katamanin O, Schwappach B, Jakob U (2022) From guide to guard – Activation mechanism of the stress-sensing chaperone Get3. Mol Cell 82(17):3226-3238.e7

  • Meredith JD, Chapman I, Ulrich K, Sebastian C, Stull F, Gray MJ (2022) Escherichia coli RclA is a highly active hypothiocyanite reductase. PNAS Jul 26;119(30):e2119368119

  • Ulrich K, Schwappach B, Jakob U (2020) Thiol-based switching mechanisms of stress-sensing chaperones. Biol Chem 402(3):239-252

  • Becker SH, Ulrich K, Dhabaria A, Ueberheide B, Beavers W, Skaar E, Iyer L, Aravind L, Jakob U, Darwin KH (2020) Mycobacterium tuberculosis Rv0991c is a novel redox-regulated molecular chaperone. mBio 11(4):e01545-20

  • Bazopoulou D, Knoefler D, Zheng Y, Ulrich K, Oleson B, Xie L, Kim M, Kaufmann A, Lee Y, Dou Y, Chen Y, Quan S, Jakob U (2019) Developmental ROS individualizes organismal stress resistance and lifespan. Nature 576 (7786): 301-305

  • Ulrich K and Jakob U (2019) The role of thiols in antioxidant systems. Free Radic Biol Med 140: 14-27

  • Currier R B*, Ulrich K*, Leroux A E*, Dirdjaja N, Deambrosi M, Bonilla M, Ahmed Y L, Adrian L, Antelmann H, Jakob U, Comini M A, Krauth-Siegel R L (2019) An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone. PLoS Pathog 15(9):e1008065

  • Ebersoll S, Musunda B, Schmenger T, Dirdjaja N, Bonilla M, Manta B, Ulrich K, Comini M A, Krauth-Siegel R L (2018) A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes. Redox Biol15:532-547

  • Ulrich K, Finkenzeller C, Merker S, Rojas F, Matthews K, Ruppert T, Krauth-Siegel R L (2017) Stress-induced protein S-glutathionylation and S-trypanothionylation in African trypanosomes – a quantitative redox proteome and thiol analysis. Antioxid Redox Signal 27(9): 517-533

  • Preveti S, Ettari R, Cosconati S, Amendola G, Chouchene K, Wagner, A., Hellmich, U A, Ulrich K, Krauth-Siegel R L, Wich P R, Schmid I, Schirmeister T, Gut J, Rosenthal P J, Grasso S, and Zappalà M (2017) Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs). J Med Chem 60(16): 6911-6923

  • Diederich K and Krauth-Siegel R L (2016) Trypanothion – Wunderwaffe und Achillesferse der Trypanosomatiden. Biospektrum 22(4): 344-347

  • Rahbari M*, Diederich K*, Becker K, Krauth-Siegel R L, Jortzik E (2015) Detection of thiol-based redox switch processes in parasites - facts and future. Biol Chem 396(5): 445-63

  • Poenisch M, Metz P, Blankenburg H, Ruggieri A, Lee JY, Rupp D, Rebhan I, Diederich K, Kaderali L, Domingues F S, Albrecht M, Lohmann V, Erfle H, Bartenschlager R (2015) Identification of HNRPK as regulator of hepatitis C virus particle production. PLoS Pathog 11 (1): e1004573